First results of the collaboration between Olon Group, Biosphere and the University of Amsterdam on biocatalysis project

One year after the launch of the International Network for Biocatalysis, an innovative scientific platform for the study and development of new industrial applications of biocatalysis, Olon, the Biocatalysis research group from the University of Amsterdam’s Van ‘t Hoff Institute for Molecular Sciences HIMS and Biosphere jointly present the results obtained and announce that their cooperation has achieved the goal of developing a new production process through the engineering of the target enzyme, which has given extremely positive conversion results.

The effectiveness of the enzyme in the conversion of ketoacid to the corresponded unnatural aminoacid useful as key starting material for the production of an Active Pharmaceutical Ingredient, was substantiated by the significant metrics measuring complete conversion; the supporting data are: target minimum enantiomeric purity required 99.7%, enantiomeric purity obtained > 99.9%